benefits of therapeutic cloning

Maga EA, Shoemaker CF, Rowe JD, BonDurant RH, Anderson GB, Murray JD. 2020;16:42733. Reprod Fertil Dev. Stem cell therapies and benefaction of somatic cell nuclear transfer cloning in COVID-19 era. 2020;20. With in vitro fertilization, however, out of the numerous embryos inseminated, only a scarce amount is used. 2020;20:2858. 2020;11:114. Human Cloning Pros & Cons | What is Human Cloning? - Video & Lesson Int J Cell Biol. 4. B. Proc Natl Acad Sci U S A. 1. The increasing use of science today is slowly leading to the development of, There are many arguments against cloning. Cloning is by no means the first technology that has been widely debated. Publication types Review MeSH terms Animals Animals, Genetically Modified Cloning, Organism* Embryo, Mammalian / physiology Embryonic Development Though this may not always come to mind, there are people out there who believe using embryonic stem cells violates the Nuremburg Code, which was established after World War II. 2020;21(7):2314. https://doi.org/10.3390/ijms21072314. Leon Kass explains that people might also seek human cloning to substitute for a dear relative (149). Sadeghi S, Soudi S, Shafiee A, Hashemi SM. Tsiapalis D, ODriscoll L. Mesenchymal stem cell derived extracellular vesicles for tissue engineering and regenerative medicine applications. 1. 2020;262:118493. https://doi.org/10.1016/j.lfs.2020.118493. Cloning has caused a number of arguments. Cloning (Stanford Encyclopedia of Philosophy) 2018;172:881-887.e7. Do you have a 2:1 degree or higher? Zhang FQ, Jiang JL, Zhang JT, Niu H, Fu XQ, Zeng LL. Biol Reprod. ODriscoll L. Expanding on exosomes and ectosomes in cancer. Feasibility of mesenchymal stem cell therapy for COVID-19: a mini review. This could result in the destruction. The . Having the prospect of being able to save lives on a regular basis shows therapeutic cloning is more advantageous than harmful. The procedure involves the combination of the patient's enucleated egg and somatic cell . presymptomatic genetical testing, or human therapeutically cloning) will very likely diminish with time, as the products of molecular medicine range further away from establishing pure diagnostic and into therapy. 1. Singh, B., Mal, G., Verma, V. et al. The Benefits of Therapeutic Cloning Imagine being able to cure Parkinson's Disease, Multiple Sclerosis, or Alzheimer's disease, maybe even being able to cure diabetes. Wu DY, Zhang X, Miao YL. Chen Y, Zhang Q, Peng W, Liu D, You Y, Liu X, et al. Ramezankhani R, Solhi R, Memarnejadian A, Nami F, Hashemian SMR, Tricot T, et al. 2020;49:7458. 2020;5(1):172. https://doi.org/10.1038/s41392-020-00286-5. Laible G, Cole S, Brophy B, Maclean P, How Chen L, Pollock DP, Cavacini L, Fournier N, De Romeuf C, Masiello NC, Gavin WG, Wells DN, Meade HM. 1. Here you can choose which regional hub you wish to view, providing you with the most relevant information we have for your specific region. In the novel, Frankenstein, Mary Shelley understood the consequence of associating technology and science. Therapeutic Cloning Front Immunol. Zhu Y, Geng S, Li Q, Jiang H. Transplantation of mesenchymal stem cells: a potential adjuvant therapy for COVID-19. Part of 2020;8:602647. https://doi.org/10.3389/fcell.2020.602647. Apart from paving the ways to augment stem cell research and therapies, somatic cell nuclear transfer (SCNT) holds unique ability for a wide range of health applications such as patient-specific or isogenic cells for regenerative medicine and breeding transgenic animals for biomedical applications. 2020;369(6511):1603-1607. https://doi.org/10.1126/science.abc4730. Therapeutic cloning in the context of cell replacement therapy holds a huge potential for de novo organogenesis and the permanent treatment of Parkinson's disease, . Nat Rev Drug Discov. Human cloning have drawn peoples attention because people are become more concerned about health problems and tried to find a methodology that can help them live longer and better; human cloning seems to be one of the possible choices. This field is for validation purposes and should be left unchanged. Production of pharmaceutical proteins by transgenic animals. Tissue Eng - Part B Rev. https://doi.org/10.1007/s12015-020-10033-6. Abbaspanah B, Abroun S, Zarrabi M, Mozdgir A, Mollanouri M. Stem cell therapy: a promising approach in treatment of COVID 19. 2020;11:1512. https://doi.org/10.3389/fimmu.2020.01512. The therapeutic cloning is a technology used the somatic cell nuclear transfer (SCNT) method to provide new cells and tissue. There is a slight difference in genetic enhancing and cloning. Trends Mol Med. Lancet Respir Med. Shu L, Niu C, Li R, Huang T, Wang Y, Ji N, et al. Therapeutic modalities and novel approaches in regenerative medicine for COVID-19. Gentile P, Sterodimas A, Pizzicannella J, Calabrese C, Garcovich S. Research progress on mesenchymal stem cells (MSCs), adipose-derived mesenchymal stem cells (AD-MSCs), drugs, and vaccines in inhibiting COVID-19 disease. Han Y, Duan X, Yang L, Nilsson-Payant BE, Wang P, Duan F, et al. Direct reprogramming of fibroblasts via a chemically induced XEN-like state. Hear Lung. Human embryos have only been claimed to be successfully cloned a handful of times, and therapeutic cloning is still in the initial phases of development. There is the chance that cloning may be able to better how humans live. Cao Y, Wu H, Zhai W, Wang Y, Li M, Li M, et al. Hum Genomics. Scientist Michael J. Sandel states "To look at the argument from the opposite end, if the creation and sacrifice of embryos in IVF is morally acceptable, why isn't the creation and sacrifice of embryos for stem cell research also acceptable? Victor couldnt live a normal life because he would always be terrified that the monster will kill him. Enhancing induced pluripotent stem cell generation by MicroRNA. Generation of marker-free pbd-2 knock-in pigs using the crispr/cas9 and cre/loxp systems. This is known as cloning. A safety consideration of mesenchymal stem cell therapy on COVID-19. This research was supported by the Deanship of Scientific Research, Imam Mohammad IbnSaud Islamic University (IMSIU), Saudi Arabia, Grant No. 2019;2045:27181. Respecting the forest may be consistent with using it, but the purposes must be weighty and appropriate with the wondrous nature of the thing" (Sandel, 2005, p. 241-247).There is no doubt embryos deserve respect, but said respect does not mean they cannot be used to help people when they are crucially needed. Harrell CR, Jovicic BP, Djonov V, Volarevic V. Therapeutic potential of mesenchymal stem cells and their secretome in the treatment of SARS-CoV-2-induced acute respiratory distress syndrome. Production and processing of milk from transgenic goats expressing human lysozyme in the mammary gland. Although human cloning serves as an aid to the children and parents with conflicts, cloning is completely unacceptable to convey human life as a product. Int J Mol Sci. Cloning can be a bad thing in many ways. I will be covering some of those ways in this paper. Int Immunopharmacol. https://doi.org/10.1128/JVI.00940-20. Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia. 2020;48:300060520955063. https://doi.org/10.1177/0300060520955063. If the cloning of a human is no longer a fantasy, it would be one of the most terrifying disasters in history. CAS Environ Res. Patra R, Chandra Das N, Mukherjee S. Targeting human TLRs to combat COVID-19: a solution? 2020;121:84752. This type of cloning is used to create stem cells cells that can, in theory, develop into any kind of cell. Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9. Basiri A, Pazhouhnia Z, Beheshtizadeh N, Hoseinpour M, Saghazadeh A, Rezaei N. Regenerative medicine in COVID-19 treatment: real opportunities and range of promises. statement and PLoS One. Curr Opin Genet Dev. ISBN: 978-3-030-21309-1. Cloning has opened the doors and provided optional ways to resolve various world problems. 2017;357:13037. Google Scholar. Some of studies show that scientists successfully cloned animals such as cows, Pigs, and sheep. FASEB Bioadv. Leon R. Kass bases his argument on repugnance in his article The Wisdom of Repugnance. 2020;53. In the future, therapeutic cloning will bring enhanced possibilities for organ transplantation, nerve cells and tissue healing, and other health benefits. Human Cloning Human Cloning comes with two dangerous processes, reproductive cloning (the creating of a new organism) and the therapeutic cloning (the creation of a new tissues or other biological products) which affects the ethics of human society. Terms and Conditions, However, there are two significant things that since the dawn of time, people always desired to dominate: time and death. Numerous pieces of technology, which can be deadly, are being made daily. eCollection 2020. 2015;3(1):2432. 2016;7:12331. the medical benefits that could be gained from treatments based on therapeutic cloning outweigh the ethical dilemma and calls for further improvements to be clinically . Both therapeutic and reproductive cloning are dangerous. Chung YG, Seay M, Elsworth JD, Eugene RD. Market M, Angka L, Martel AB, Bastin D, Olanubi O, Tennakoon G, et al. Therapeutic cloning is something that should get more recognition because the good it can do. 2014;11:11421. Nature. Ray S, Rajarshi K, Chatterjee A. Combating COVID-19 with mesenchymal stem cell therapy. When one looks closely at both processes, they see the processes are quite similar. https://doi.org/10.1038/s41586-020-2708-8. Google Scholar. Despite medical benefits and advancement of, Introduction Therapeutic Cloning a. Cloned embryos are used to get stem cells from them for research and therapeutic usage. Systemic administration of human umbilical cord-derived mesenchymal stem cells effectively ameliorates the outcomes of a critically ill elderly patient with COVID-19 with multiple comorbidities: a case report. Reproducing a human being or an animal the normal way is free. Tachibana M, Amato P, Sparman M, Gutierrez NM, Tippner-Hedges R, Ma H, et al. All authors contributed to the conception and the main idea of the work. Klimczak A. Perspectives on mesenchymal stem/progenitor cells and their derivates as potential therapies for lung damage caused by COVID-19. Stem Cell Investig. The use of mesenchymal stromal cells in the treatment of coronavirus disease 2019. Curr Stem Cell Res Ther. She warns us with a dying Frankenstein telling Walton, seek happiness and tranquility and avoid ambition, even if it only be the apparently innocent one of distinguishing yourself in science and technology (Shelley 162).
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